A recent study by the University of Cape Town’s Centre for Pharmacy Medicine (CPM) and National Institute of Health (NIH) has shown that people who use Nexium (esomeprazole) are not at risk of developing heart attacks or strokes.
The study, published in theNew England Journal of Medicine(NIMJ) shows that those who take Nexium for the first time are not at risk of developing a heart attack or stroke. However, those who have used Nexium for a long time were also at a lower risk of developing heart failure, the researchers wrote.
“This highlights the need for additional studies to determine the long-term risk,” Dr. Michael S. Reilley, director of the CPM, told the newspaper. “This study suggests that these patients may be at greater risk of developing heart failure as a consequence of taking Nexium for a longer time.”
Nexium is one of the most widely prescribed proton-pump inhibitors (PPIs) for the treatment of gastroesophageal reflux disease (GERD), also known as peptic ulcer disease. PPIs are used for treating the symptoms of acid reflux, which include acid reflux and heartburn.
Nexium was first approved by the U. S. Food and Drug Administration (FDA) in 1997 for the treatment of acid reflux. It is now the only PPI approved to treat GERD.
The FDA approved Nexium in 2009 for the treatment of GERD. The drug works by blocking acid production in the stomach and esophagus. In patients with severe GERD, Nexium is often used to reduce acid production and prevent the acid from being refluxed out of the esophagus. The drug is available in many strengths and is used only when directed by a gastroenterologist.
The CPM and NIH conducted a study looking at the effects of Nexium on the safety of esomeprazole, an oral anti-emetic medication used to treat acid reflux. The researchers looked at all patients with an esomeprazole dose of 50 mg, taken as needed once a day. They looked at their medical records to determine if Nexium was associated with an increased risk of heart attacks, strokes, and death.
A total of 4,934 people were screened, of which 2,078 (9.4%) developed heart attacks or strokes. Of those, 2,078 (9.4%) developed heart failure.
A total of 653 people who were also taking Nexium were followed up for another 4,086 cases of heart failure. Nearly 2,000 people who took Nexium for a longer time, in particular those who had taken Nexium for years or longer, were more likely to develop heart failure. Of the 4,086 people, 2,078 developed heart failure.
The researchers noted that the study did not find a link between the use of Nexium and an increased risk of heart failure. They added that the data from the study should be interpreted with caution and that patients with a history of heart failure should be monitored closely for the occurrence of any complications.
“While we do believe that the increased risk of heart failure in patients taking Nexium is due to reduced acid production, the data does not support that the risk is increased in those taking the drug,” Reilley said.
In addition to the CPM and NIH, the researchers also wrote that the results should be interpreted with caution and that patients should be monitored closely for any adverse effects. The study did not show a link between Nexium and a heart attack or stroke.
Nexium is now available in all over the world, including the United States. The CPM has been in use for over 25 years and the NIH has been in use since 2009. Both CPM and NIMJ found that people who used Nexium for the first time were at higher risk of developing a heart attack or stroke than people who were not taking it.
Reilley told the newspaper.
The authors of the CPM’s paper also called for additional studies to determine the long-term risk, the paper added.They also said that the results should be interpreted with caution and that patients should be monitored closely for any complications.
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AllOurBrandNameDrugs is a licensed US pharmacy. We provide trusted sources for all your medication needs. With over 15 years of customer support and a high success rate, AllOurBrandName is a trusted source for AllOurBrandName medication. We can help you with any questions or concerns you may have. Just check the order form, prices, and shipping information above. Id your answer to our most popular brands.Nexium 24 Hour Heartburn Relief Medicine is an extended-release acid and diuretic medicine that is taken before sexual intercourse to reduce the risk of acid-related stomach discomfort. It is taken at least three days a week.
Nexium 24 Hour Heartburn Relief Medicine may take one to 14 days for full symptom response. Do not take more than this way will not be effective in managing the full range of symptoms of GERD.
Tell your doctor if you have not had anything severe like esophag cancer or stomach ulcers, heartburn is a symptom of GERD. They can assess your GERD and provide you with tests to make sure you are risk free. They also may send you to a treatment like Nexium 24 Hour Heartburn Relief Medicine for a little relief. Just be aware that Nexium 24 Hour Heartburn Relief Medicine is not a cure for GERD and helps to slow down. You may be at risk of developing it. If you are interested in taking Nexium 24 Hour Heartburn Relief Medicine for heartburn, you will need a few things:
If you are allergic to esomeprazole, any of the other gastric medicines, or any other ingredients of the medicine, esomeprazole may cause your indigestion. You can also take esomeprazole with or without food. This will prevent it from having an effect on your indigestion. If you get it, you may take it for 4 to 8 days and send your doctor or pharmacist in the future visit 1-2 stomach pains (or more frequent than that, like, three or more times a week). You can take it for a longer term, like for a longer time, but you will have reduced or unchanged heartburn in the future. Just be aware that esomeprazole may reduce the absorption of magnesium in the body.
It will help if you are taking a low dose (a day or two before having sex) of a medicine like esomeprazole 24HR or esomeprazole 24HR at the same time as the acid and diuretic medication:
You should be at a reduced risk of getting heartburn with this medicine, which is similar to using an acid and diuretic medicine like: using an acid and diuretic medicine like Nexium 24HR, taking it for a longer term, like for a longer time, like for a longer time, like for longer, you will be reduced or unchanged heartburn in the future.
Take one Nexium 24HR and one acid and diuretic 24HR at the same time as the acid and diuretic medicine: Take one tablet about an hour before you have sex, take one tablet an hour before sex, take one tablet an hour after sex, take one tablet an hour after sex an hour before sex an hour before sex. If you take one tablet an hour before sex, and one tablet after, take the medicine on an empty stomach for best results.
Wash your hands before you chew, cut, or swallow the medicine.
Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
Mud's urineStomach Pain, Nausea, vomiting, Skin reactions, Liver problems Magnesium
This medicine can cause diarrhea.
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